Will software engineering profession die in the age of AI? IBM stock bleeds as Claude Code writes COBOL scripts. What it means for techies

AI agents like Claude Code are reshaping software development by automating legacy modernisation and routine coding. A recent ...
InfoQ

Microsoft Agent Framework RC Simplifies Agentic Development in .NET and Python

Microsoft has announced that the Microsoft Agent Framework has reached Release Candidate status for both .NET and Python. This milestone indicates that the API surface is stable and feature-complete ...
The BMJ

Adherence to legislation and recommendations to publicly post protocols and results of post-authorisation studies registered with European Medicines Agency: cross sectional study

Objective To assess whether post-authorisation studies registered with the European Medicines Agency (EMA) adhere to legislation and recommendations to publicly post study protocols and results.
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
Nature

Predicting protein function from sequence and structure

'Inheritance through homology' is the most common and generally more accessible approach to function prediction, but orthology should be established where possible to improve confidence in predictions ...