PKM2 acts like a switch for cellular energy, directly determining whether cancer cells can rapidly generate energy and biosynthetic precursors to support their continued growth. Using a driving ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

When a maize plant is attacked by the fungus Ustilago maydis, tumor-like tissue growths occur at the site of infection. How the pathogen causes this response in its host has long been unknown. But a ...

Dry eye disease affects millions of people, causing burning, redness, and constant eye fatigue that can worsen over time. Scientists now believe the problem may begin deep inside tear glands, where a ...

Researchers have determined that condensates are electrically charged droplets that can induce voltage changes across the ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

A Cedars-Sinai study has identified a previously unknown role for astrocyte cells in how the brain responds to damage and ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

Life’s fundamental structure is the cell, and so the main things that a cell does — processing biomolecules, growing, replicating its genetic material and producing a new body — are considered ...

Researchers have uncovered a shared brain cell breakdown mechanism behind Alzheimer’s and Parkinson’s diseases, revealing how two different proteins can disrupt neurons in the same devastating way.

Using single-cell transcriptomic data from adult mouse inner ear hair cells, the authors identify the differences and similarities of the four hair cell types. They make an important finding: that ...

The tectorial membrane (TM) is a critical component in the auditory system, playing a pivotal role in stimulating hair cells and facilitating sound transmission. Abnormalities in the TM are commonly ...