Why most people fail at fitness, according to biohackers — and the tricks they use to keep on track

If you’re substantially overweight and you’re relying on willpower and effort to lose the weight, the odds are very high that ...
eLife

Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...