Thymocyte selection and differentiation requires extracellular signal–regulated kinase (Erk) signaling, but transcription factor substrates of Erk in thymocytes are unknown. We have characterized the ...
The extracellular domain of SAP-1 extends into the intestinal lumen and its active tyrosine phosphatase domain resides in the cytoplasm. SAP-1 is thought to inhibit the development of colitis by ...
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