Nature

The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma

It has been well documented that IL-6 and IGF-1 are major growth factors in the bone marrow microenvironment of MM. 25, 26 These two cytokines confer growth advantage and increase drug resistance via ...
ascopubs.org

A first-in-human phase I study to evaluate the pan-PI3K inhibitor GDC-0941 administered QD or BID in patients with advanced solid tumors.

Assessment of circulating tumor cell (CTC) patterns among disease-free breast cancer patients vaccinated with adjuvant HER2/neu-based peptide vaccines. Background: The PI3K-PTEN-AKT signaling pathway ...
ascopubs.org

Activity of GDC-0941, an inhibitor of phosphoinositol 3 kinase (PI3K), in gastrointestinal stromal tumor (GIST) xenograft and duration of response after discontinuation of ...

Correlation of the topography of KIT exon 11 mutation with primary GIST location and predictive value for PFS in patients with advanced GIST: Results from the BFR14 randomized phase III trial of the ...
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China Mobile Ltd (0941) China Mobile Ltd stock price live, this page displays HK 0941 stock exchange data. View the 0941 premarket stock price ahead of the market session or assess the after hours ...