Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves. "Because tRNA ...

Loss of TRMT10A led to a decrease in the levels of initiator methionine tRNA (tRNA iMet) and a specific glutamine tRNA (tRNA Gln). This reduction weakened the initiation of protein synthesis for ...

Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the development of a new method for simultaneously synthesizing all transfer RNA (tRNA) ...