An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

Co‑injecting three common amino acids with LNPs dramatically boosted both mRNA delivery and CRISPR gene editing efficiency in preclinical models.

RNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ...

Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...

Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular ...

In two experiments, researchers have found that introducing people to "mental models" about how mRNA vaccination works and how the body protects itself from foreign DNA can preemptively or reactively ...

mRNA (red) is transported from the cell nucleus to the cytosol though a nuclear pore in complex with several proteins (white), including a helicase, Tap and Rae1, which interacts with the nucleoporin ...

Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...