Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

A recent international research project has used advanced microscopy techniques and computational modeling to discover why ...

Researchers have used advanced microscopy and computational modeling to show how herpesvirus infection affects host-cell nucleus structure.

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...