Oocytes are arrested for long periods of time in the prophase of the first meiotic division (prophase I). As chromosome condensation poses significant constraints to gene expression, the mechanisms ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...

New Rochelle, NY, July 3, 2018-The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for ...

Human oocytes can last for up to 50 years—and a newly discovered metabolic pathway is key to this longevity. By Lauren J. Young Published Jul 22, 2022 2:45 PM EDT Get the Popular Science daily ...

A human female is born with all the egg cells she will ever have. The possibility for the development of new oocytes is zero. Given this constraint, it is crucial that these gametes remain healthy and ...

ELVAs pictured under a microscope. The ‘superorganelle’ roams the cytoplasm, capturing and holding onto toxic protein aggregates to protect oocytes from their toxic effects. Oocytes are immature egg ...