Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as ...
Duke Human Vaccine Institute (DHVI) investigators used a technique called time-resolved, temperature-jump (TR, T-Jump) small-angle x-ray scattering (SAXS) to capture the spectacularly brief moment ...
As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there’s a spectacularly brief moment in which a tiny piece of its surface snaps open to ...
Most people infected by the hepatitis C virus (HCV) can be cured with antiviral therapy, but access to the treatment remains limited. Even diagnosis of hepatitis C, a disease that causes chronic ...
First-ever biologically authentic computer model was completed of the HIV-1 virus liposome. Key finding from the simulations is the formation of sphingomyelin and cholesterol rich microdomains. HIV-1 ...
Seeing a glycoprotein on the envelope of the HIV virus snap open and shut in mere millionths of a second is giving investigators a new handle on the surface of the virus that could lead to broadly ...