Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...
The human brain is known to store various memories for long periods of time, progressively learning from new experiences and forming adaptive representations that ultimately guide decision-making and ...
A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...
Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...
A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...
New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...
Recently, researchers from the University of Queensland (Australia) and the Wicking Dementia Research and Education Centre at the University of Tasmania investigated the effects of rTMS on synapses in ...
Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...
This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...
Researchers are testing a new approach to repair early memory loss by protecting brain connections affected in Alzheimer’s ...
As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...