Epstein-Barr virus infection induces the upregulation of glycolysis in intestinal macrophages, which subsequently activates Gasdermin D, NLRP3, interleukin-1β, and interleukin-18 in macrophages within ...

Biotechnology Co. Ltd. has disclosed pyroptosis and NLRP3 inflammasome inhibitors reported to be useful for the treatment of cancer, type 1 diabetes, gout, inflammatory disorders, multiple sclerosis, ...

Ulcerative colitis, one type of chronic inflammatory bowel disease, is driven by a form of programmed cell death called pyroptosis.

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of ...

The inflammasome, a multiprotein complex, plays a crucial role in the field of innate immunity. It is activated by ...

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment. Characterized by cell swelling and the formation of "bubble" structures, ...