A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...
A single damaged protein inside one brain cell may seem insignificant. Yet new research shows how that small mistake can ...
Dry eye disease happens when the lacrimal glands do not make enough tears, or the tears do not have the right balance of ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Seed round co-led by Elaia, Pfizer Ventures and Bpifrance Machine-learning platform enables signal peptide-informed discovery of small molecules that selectively inhibit protein secretion allowing for ...
snoRNAs were thought simply to guide chemical modifications to rRNAs, but a new technique has revealed a suite of potential functions in protein secretion. A recent research effort from the University ...
They found a protein called cathepsin S present only in the tears of patients with Sjogren's syndrome, and in a new study in the American Journal of Physiology—Cell Physiology, link its presence to ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
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