Variegate porphyria (VP) is an autosomal dominant condition that results from the deficiency of protoporphyrinogen oxidase (PPOX, EC 1.3). The build-up of porphyrin precursors delta-aminolevulinic ...

This page lists all known medications that could potentially lead to 'Variegate porphyria' as a side effect. It's important to note that mild side effects are quite common with medications. The ...

Porphyria cutanea tarda (PCT) is the most common porphyria, a group of acquired or genetic disorders of heme biosynthesis with cutaneous and/or systemic manifestations. [1] Classic PCT presents with ...

Use of the RNA inhibitor givosiran was shown to reduce expression of delta-aminolevulinic acid synthase 1, in turn reducing the severity of acute attacks and chronic symptoms for patients with severe ...

Please provide your email address to receive an email when new articles are posted on . Clinicians are hoping an RNA interference therapeutic targeting aminolevulinic acid synthase 1, known as ...

Haemoglobin is protein found in red blood cells that carries oxygen, it also gives the red color. Now how is it related to the genetic disorder like Porphyria? Porphyria is a group of rare genetic ...

Acute porphyrias are rare genetic disorders that present with neurologic and systemic symptoms, including abdominal pain, hyponatremia and seizures. When porphyria is suspected, a urine screening ...

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

Acute hepatic porphyria, or AHP, is a group of rare genetic conditions that affect how the body makes a natural substance called heme. Heme is produced in the liver and is essential for many important ...