Recent reports of patients failing to respond to ivermectin, the standard drug for treating river blindness (onchocerciasis), have suggested the emergence of drug-resistant Onchocerca volvulus (the ...

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels. The Food and Drug Administration (FDA) has approved ...

Scientists have for the first time fully sequenced the genome of onchocerca volvulus, the parasitic worm that causes river blindness. This has allowed them to identify a number of proteins that could ...

This case-series describes the 6 human infections with Onchocerca lupi, a parasite known to infect cats and dogs, that have been identified in the United States since 2013. Unlike cases reported ...