The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Chargers and Denver Broncos.

The Seahawks will play their most important game of the season in Week 18. Here are 3 Seahawks bold predictions against the 49ers.

The NFL weekend delivered plenty of drama in Week 17. A surprising Pittsburgh Steelers loss to the Cleveland Browns opened the AFC North race and set up a winner-take-all finale against the Ravens in Week 18, while the Philadelphia Eagles edged the Buffalo Bills 13-12 in a defensive battle that came down to a late two-point attempt.

The good news for the San Francisco 49ers (12-4) is they’ve already beaten the Seattle Seahawks (13-3) one this season.The bad news is that game was all the way back in Week 1, and the Seahawks have won 13 of their last 15 games since then.

For some, this year is already over and it's all about the upcoming 2026 offseason, and more importantly, the draft. Week by week, more teams will fall into this area, making where their selection sits in Round 1 all the rage.

The 2025-26 NFL regular season concludes with the Week 18 NFL schedule, which begins with a pair of games on Saturday. Tampa Bay hosts Carolina at 4:30 p.m. ET, while San Francisco and Seattle meet in an NFC West battle at 8 p.

The Houston Texans could clinch their first 12-win season under DeMeco Ryans with a victory over the Colts on Sunday at NRG Stadium.