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NFL Week 18 picks, score predictions for every game this week, including Lions-Bears, Chargers-Broncos, Colts-Texans, Ravens-Steelers, Seahawks-49ers.
It's Week 18 of the 2025 NFL season and the regular season comes to a close with plenty to play for around the league. The action starts on Saturday with the Carolina Panthers visiting the Tampa Bay Buccaneers with the NFC South on the line and wraps up Sunday night with the Pittsburgh Steelers hosting the Baltimore Ravens for the AFC North title.
NFL playoff picks: Rams at Panthers | Packers at Bears | Bills at Jaguars | 49ers at Eagles | Chargers at Patriots | Texans at Steelers | The Republic's score predictions | Win probabilities | Super Bowl projection
The NFL playoff picture will finalize after the NFL Week 18 schedule. The top seeds in both the AFC and NFC are still at stake, as is who is going to take the NFC South and AFC North title and the playoff spot that comes with it.
Some of the site's predictions differ from NFL Week 17 odds and other NFL Week 17 picks for NFL Week 17 games. How correct will the analytics be this week? Click on each game for more NFL Week 17 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.
Office Pool – NFL Game Picks Our staff will pick the winner of every NFL contest every week. They will also rank their confidence level in their selection, ranging from 1 (least confident) to 16 (most confident). We'll also combine everyone's confidence points, giving you a Wisdom of the Staff confidence level as well.
It's true the Titans secondary is occupied by practice squad players, but 13.5 points is a lot. I'm not calling for an upset, but don't forget that this Jaguars team has lost to the Titans in a critical Week 18 spot before.
After 272 regular season games, the 2026 NFL playoffs have arrived, starting with Wild Card Weekend. Seven teams that made the postseason as
The Underdog promo code NEWSWEEK will introduce a $75 bonus to new users for NFL Wild Card, NBA, and CFP picks this week.
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