NF-κB signalling is a central regulator of immune responses, orchestrating the expression of genes that control inflammation, cell survival and proliferation. T cell activation, triggered by antigen ...

AMES, Iowa – A decade ago, Raquel Espin Palazon discovered that inflammatory signaling pathways must switch on for embryos to produce blood stem cells. The latest work from her lab shows the potential ...

For some diseases, a few vaccine doses enable lifetime immunity. But influenza requires annual vaccines to maintain immunity. One reason is because lung T cells only live for a few months.

A research team has discovered when and why inflammatory signaling affects the formation of blood stem cells in embryos, which will benefit efforts to develop lab-grown, patient-derived stem cell ...