A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Integrated screening and CRISPR reveal eleven previously unknown factors essential for early embryo development. They showed ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Infertility is a major healthcare concern. Understanding the molecular regulators governing fertilization, early embryonic ...

NYU Langone’s Advanced Rodent Transgenics Laboratory assists researchers in generating mutant mice for experimental use.

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

Scientists have engineered a hybrid mouse with a gene that predates all animal life. The team replaced a single gene in the mouse stem cells with a version from an ancient, single-celled ancestor, and ...

Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...