In several recent publications the term ‘molecular karyotyping’ was adopted to describe the use of microarrays for detecting genomic imbalances, in analogy to conventional karyotyping based on ...

A Phase I/II randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that ...

In several fields including environmental monitoring, food manufacturing, and biomedical research, the ability to perform accurate measurements is key to a variety of studies. Whilst it is sufficient ...

Microarray Technology evolved from the initial report in the mid 1970s that labeled nucleic acids could be used to monitor the expression of nucleic acid molecules attached to a solid support occurred ...

JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on a ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the ...