Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer ...

Chronic activation of the stress protein ATF6α promotes aggressive liver tumors by rewiring glucose metabolism and ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key ...

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells ...

The integration of single-cell and spatial transcriptomics with advanced metabolic profiling tools has revolutionized the ...

Dr. Maik Luu discusses how postbiotics can be used to reprogram CAR T cells to promote anti-tumor function and what further research is needed to bring probiotic-boosted therapies to the clinic.

In order for heart and vascular cells to develop properly and remain healthy for a long time, many processes in the cells ...