Fatty liver disease isn’t just a concern for the overweight—it can strike people of healthy weight and diet, and now scientists think they know why. Two genes previously linked to cancer, RNF43 and ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

Scientists identify measurable cellular changes that flag higher cancer risk more than a decade before tumors appear. In A ...

Scientists have found that combining silybin with carvedilol works far better against liver fibrosis than either drug alone.

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, ...

Organoids refer to small-scale organs made up of diverse cell types, exhibiting structures and functions akin to actual organs. Unlike conventional cell cultures, organoids better replicate human ...

The FDA has qualified its first artificial intelligence tool to help drug developers evaluate fatty liver disease in their clinical trials. The agency gave a green light to the AI-Based Histologic ...

As drugmakers race to join the obesity drug market ignited by the approval of Wegovy and Zepbound, they’re not just competing on their drugs’ weight loss effects. They’re also competing on their ...

Dr. Saurabh Sethi notes that most people believe sugar affects weight. However, it can strongly influence your liver.

Drugs that fail in late stages of development create one of the biggest challenges in global healthcare. In fact, less than 10% of the drugs that move into clinical development survive to approval.