As our primary interface with the outside world, the skin needs to be able to protect itself against infectious threats. Specialized cells known as Langerhans cells (LCs) (see image) are an essential ...

Researchers at Ben-Gurion University of the Negev (BGU) have discovered that a gene long known for shaping the skin's ...

More than half-a-century after the fact, it’s still the look in his father’s eyes that John Langerhans remembers. It was a look that led Langerhans to a lifetime of playing and coaching baseball, ...

A nationwide team led by researchers at Baylor College of Medicine, Texas Children’s Hospital and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell ...

Langerhans cells (LCs) are a type of dendritic cell that characteristically express S100, CD1a, and langerin (CD207) and contain ultrastructural Birbeck granules. LC histiocytosis is a neoplastic ...

The occurrence of graft-versus-host disease (GVHD) in the skin of patients receiving bone-marrow transplants is a common and serious complication, hindering the widespread use of this procedure.

Some people might say that Paul Langerhans Jr. was destined to make many contributions to medicine because he was born into a family of physicians and scientists. He made his first major contribution ...

Researchers at Yale School of Medicine have demonstrated that Langerhans cells in the skin, which had been thought to alert the immune system to pathogens, instead dampen the skin's reaction to ...

Fifty-four patients from 12 countries took VMF 20 mg/kg/d. They were classified according to risk organ involvement: liver, spleen, and/or blood cytopenia. The main evaluation criteria were adverse ...

Positron-emission tomographic (PET) images show a single bone lesion involving the humerus (Panel A, arrow); low-risk lesions involving the orbit, lymph nodes, bone (multifocal lesion), and thymus ...

Researchers found that Langerhans cells (LCs) play a crucial role in mucocutaneous acute guest-versus-host disease (aGVHD). Their experiments in mice showed that when the LCs of a recipient were ...

We report an unusual case of Langerhans cell granulomatosis (LCG) manifested as a villous synovial proliferation in a 38-year-old female jogger. One year after the onset of joint symptoms, she had a ...