Osaka, Japan – The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle ...

Thousands of our cells successfully divide every day. They replicate their DNA and then separate so that each of the new cells has the same complement of chromosomes. If the process goes wrong and ...

Researchers identify a novel centromere-specific histone H3 variant called the “CENP-A”, which reconstituted with H4 forms “CENP-A–H4” octasome and explore its role in mitosis. Centromeres, ...

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell ...