In the embryonic kidney, three types of precursor cells interact to form three-dimensional structures of the kidney: nephron progenitor cells, ureteric buds, and interstitial progenitor cells. Methods ...

A mammalian kidney contains approximately one million nephrons, which are functional units consisting of glomeruli, proximal tubules, loop of Henle, distal tubules and collecting ducts. During ...

Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for ...

The kidney is an excellent model in which to study the mechanisms of organogenesis. During kidney development, the epithelial ureteric buds branch and induce the surrounding mesenchymal cells to ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

St. Louis, Sept.8, 2003 -- By taking advantage of techniques developed in the search for Alzheimer's treatments, a team of researchers has discovered that a molecule called Notch is essential for the ...

Scientists identify a possible therapeutic target to extend kidney development in preterm babies that would reduce the risk of kidney failure later in life. Study identifies possible therapeutic ...

WINSTON-SALEM, N.C. – June 21, 2012 – Regenerative medicine researchers at Wake Forest Baptist Medical Center have reached an early milestone in a long-term project that aims to build replacement ...

The Clinical Implications of Basic Research series has focused on highlighting laboratory research that could lead to advances in clinical therapeutics. However, the path between the laboratory and ...