Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...

Using small molecules to control the function of proteins in live cells with complete specificity is highly desirable, but challenging. Here we report a small-molecule switch that can be used to ...

In December 2017, after six years of debate and discussion, the United States government closed a chapter—though perhaps not the book—on one of the most controversial experiments in the annals of dual ...