Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In ...

The intestinal parasite Cryptosporidium is a vicious trespasser, hiding within the cells that line the gut and causing intestinal damage. "Cryptosporidium infections can be life-threatening, ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal ...

Researchers have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) that reduce their ability to heal the intestine, even after inflammation has receded.

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers at the University of Helsinki have discovered a new mechanism of action between the ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it boosted regeneration, reduced inflammation, and improved nutrient absorption, ...

Hang Zhao, Lin Shi, Zhengran Li, Ruiyan Kong, Xuejing Ren, Rui Ma, Lemei Jia, Meifang Ma, Shan Lu, Ran Xu, Richard Binari, Jian-Hua Wang, Meng-qiu Dong, Norbert Perrimon, Zhouhua Li Proceedings of the ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts. While ISCs play an essential role in epithelial ...

Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) ...