The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

When a nasty bug infects a cell, the cell sends out riders called interferons that, like Paul Revere, warn the other cells: A virus is coming! A virus is coming! Interferons bind to receptors on the ...

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at ...