A research group at Nagoya University in Japan has successfully developed an ultrafast and simple synthetic method for producing indole derivatives. Their findings are expected to make drug production ...

Indole, and structures derived from it, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[b]indoles -- frameworks made of ...

In vivo studies have shown that indole-3-acetic acid is derived from tryptophan by at least two pathways. Tryptophan may undergo transamination to indolepyruvic acid, which in turn is degraded to ...

Indole is a ubiquitous nitrogen‐containing aromatic compound that acts both as an environmental pollutant and as a biological signalling molecule. Its inherent recalcitrance demands efficient ...

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds. Derivatives of indole, ...

A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds. Indoles, which form the backbone of many ...

A new chemical reaction pioneered by researchers from the University of Toronto (Toronto, ON, Canada) simplifies the production process for indole rings, a basic molecular frameworks commonly used in ...

The proposed method is simple, mild, fast, and produces high yields, with the potential to inspire the development of new drugs and agrochemicals. Indolo[2,3-a]quinolizidine is a common structural ...

Indole, an organic chemical compound that’s found in our gut and contributes to the smell of poop, increases the healthy lifespan of worms, flies, and mice, according to new research. Scientists say ...