It is considered potentially harmful to administer imipenem–cilastatin to patients with IgE-mediated hypersensitivity to penicillins 1 because of a 47.4 percent rate of cross-reactivity (9 of 19 ...

Imipenem 250mg, cilastatin sodium 250mg; pwd for IV infusion after reconstitution and dilution; sodium content 18.8mg (0.8mEq). Serious susceptible infections including bacterial septicemia, lower ...

Adult: IV- Susceptible infections- As imipenem: 1-2 g/day in divided doses 6-8 hourly. Surgical prophylaxis- As imipenem: 1 g on induction of anesth, followed by 1 g 3 hours later. Additional doses of ...

KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental ...

Changes Clinical Practice: Tigecycline should not be used as monotherapy in patients with ventilator-associated pneumonia (VAP). I found this article very important because it shows that tigecycline ...

Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. Adult and pediatric patients undergoing chemotherapy for solid tumors, ...

Results of a phase 2 study found that addition of relebactam, a β-lactamase inhibitor used to restore the activity of imipenem against imipenem non-susceptible pathogens, was as effective as treatment ...

Review the side-effects of Imipenem and Cilastatin as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In ...

Vol. 10, No. 4, New Developments in Resistance to β-Lactam Antibiotics among Nonfastidious Gram-Negative Organisms (Jul. - Aug., 1988), pp. 892-898 (7 pages) Emergence of resistance to imipenem during ...

Evidence was from 2 phase 3 randomised controlled trials (Motsch et al. 2020 and Titov et al. 2020) both conducted in a non-UK hospital setting. Motsch et al. (2020; n=47) compared imipenem with ...