Hydroxyurea is generally contraindicated in patients with sickle cell disease who become or plan to become pregnant, but post-marketing safety data suggest that treatment continuation is safe. The ...

Hydroxyurea remains effective over the long term among children with sickle cell disease, real-world data suggested. The average time on hydroxyurea was 5 years, with many children on the therapy for ...

(WASHINGTON, April 17, 2024) — Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new ...

Please provide your email address to receive an email when new articles are posted on . Use of hydroxyurea did not reduce ovarian reserve among girls and young women with sickle cell disease.

Please provide your email address to receive an email when new articles are posted on . Three-quarters of women who became pregnant during hydroxyurea therapy had live births. Researchers observed no ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Sickle cell disease (SCD) is a pressing global health issue, with rising cases and mortality, especially in low- and middle-income countries (LMICs). Hydroxyurea, a cost-effective treatment for SCD, ...

Machine learning identified RDW and HGB as key predictors of hydroxyurea resistance in polycythemia vera, aiding early identification and treatment adjustment. The PV-AIM study used electronic health ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...