Oxbryta (voxelotor) is a brand-name drug that’s prescribed for sickle cell disease in adults and certain children. As with other drugs, Oxbryta can cause side effects, such as headache, abdominal pain ...

Hydroxyurea was used in a 25-year-old man with SCD who had AP and recurrent SP. [21] The patient had received hydralazine, piracetam, and pentoxifylline, but the AP and SP episodes continued over the ...

Hydroxyurea is generally contraindicated in patients with sickle cell disease who become or plan to become pregnant, but post-marketing safety data suggest that treatment continuation is safe. The ...

Large European cohort data suggest hydroxyurea pregnancy exposure in sickle cell disease is not linked to congenital malformations, supporting nuanced clinical decision-making.