Purpose: The pharmacology, efficacy, dosage, adverse events, and economics of omalizumab are discussed. Summary: Omalizumab, a recombinant DNA-derived humanized monoclonal antibody, binds to the Cε3 ...

DUBLIN, Jan. 21, 2021 /PRNewswire/ -- The "Global Humanized Mice Model Market, by Service (Breeding, Model-In licensing, Genetic testing and Others), by Type, by Immune Checkpoints, by Application, by ...

In most clinical applications, the monoclonal antibodies (mAbs) used are of murine origin; however, the small spleen of the mouse is limited in its ability to generate antibodies. Also, the mice used ...

Purpose: This single-center, dose-escalation study examines the safety, efficacy, and pharmacokinetics of epratuzumab (anti-CD22 humanized monoclonal antibody) in patients with recurrent indolent ...

The FDA recently approved Imfinzi (durvalumab) for the treatment of bladder cancer, making it the fifth new monoclonal antibody approved this year. More than 20 antibodies have been approved by the ...

Recombinant antibodies (rAbs), also called genetically engineered antibodies, are produced by cloning the antibody which is made of light and heavy chain DNA sequences. In comparison to monoclonal ...

Epitomics, Inc. today announced that it has spun-out to its shareholders a new biotechnology company called Apexigen, Inc., which will focus on the development and commercialization of humanized ...

Antibodies play a vital role in the immune system by providing protection against foreign invaders, such as bacteria and viruses. Produced by B cells, antibodies are protein molecules that can be ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

Actemra®, a Humanized Anti-Human IL-6 Receptor Monoclonal Antibody Obtained Approval for Indications of Rheumatoid Arthritis, Polyarticular-Course Juvenile Idiopathic Arthritis and Systemic-Onset ...