A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...
Researchers demonstrated that declining Hedgehog signaling from Cilk1 loss produces stepwise changes in tooth formation and morphology CHENGDU, CHENGDU, CHINA ...
A hypothetical model illustrating how reduced Hedgehog signaling alters interactions between the rudimentary tooth bud (R2) and the first molar (M1), leading to supernumerary (SN) tooth or molar ...
Cilk1 deficiency disrupts normal tooth development by altering primary cilia function and weakening Hedgehog signaling. This ...
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