Recent advances in next-generation sequencing (NGS) make it possible to directly sequence genomes and exomes of individuals with Mendelian diseases and screen sequence data for causal variants. With ...

Proteins, the natural molecules that carry out key cellular functions within the body, are the building blocks of all diseases. Characterizing proteins can reveal the mechanisms of a disease, ...

Scientists at the University of Illinois at Urbana-Champaign have developed deep generative models to predict undiscovered sequences of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

Globally, biodiversity is concentrated around the equator, but the scientific institutions generating DNA sequence data to study that biodiversity tend to be clustered in developed countries toward ...

Scientists have generated the first complete DNA sequence of a human X chromosome, in a major step towards mapping the entire human genome. A team from the University of California and the National ...

For many laboratories in the developing world, lack of funding and practical experience are hurdles to generating their own DNA sequence data. However, the financial, technical, and logistical burden ...