Now a December 10, 2013, Alzheimer’s and Dementia paper openly challenges the value of the original findings for human therapy development. Researchers led by Bob Olsson and senior author Kaj Blennow ...
Figure 1: Identification of GSAP as an imatinib target. APP-CTF is cleaved by γ-secretase in the middle of its transmembrane domain to generate amyloid-β (γ-cleavage) and near its cytosolic membrane ...
Advances in Alzheimer disease (AD) research during 2010 have identified promising novel diagnostic tools and therapeutic targets for this condition, and suggest that amyloid-β immunotherapy reduces ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback