National Institute for Health and Care Excellence

EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer

The diagnostics advisory committee reviewed the evidence available on the clinical and cost effectiveness of epidermal growth factor receptor tyrosine kinase (EGFR‑TK) mutation testing to inform first ...
The American Journal of Managed Care

Clinical Advances in EGFR-Mutated NSCLC: Insights From MARIPOSA and FLAURA2

EGFR mutation testing is crucial for NSCLC treatment, but global disparities exist in access to comprehensive molecular diagnostics. Third-generation inhibitors and combination regimens improve ...
Medscape

Tests in the Works to Determine Who Will Benefit From EGFR Inhibitors

May 14, 2008 — The blocking of epidermal growth-factor receptors (EGFR) to treat non-small-cell lung cancer is becoming increasingly common, but there is considerable debate about when to initiate ...
Oregonian

Dear Doctor: How does blood test eGFR number reflect kidney function, and what range is ‘normal’?

DEAR DR. ROACH: I am a 73-year-old female. A recent blood test returned an eGFR (estimated glomerular filtration rate) of 59. My physician’s nurse told me that the test was normal. When I asked her ...
Healio

Cystatin C- and creatinine-based eGFR discrepancies linked to adverse kidney, CV outcomes

Major differences between eGFR based on cystatin C compared with creatinine were associated with higher rates for all-cause mortality, CV events and kidney failure for outpatients, according to data ...
National Institute for Health and Care Excellence

EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer

The systematic review was carried out to identify evidence on the technical performance and clinical effectiveness of the different options available to detect epidermal growth factor receptor ...