Factor V Leiden thrombophilia is a genetic disorder that increases the risk of abnormal blood clot formation. Factor V Leiden thrombophilia is a genetic condition that increases the risk of developing ...

Acquired Factor V inhibitors represent a rare and heterogeneous group of coagulation disorders, characterised by the sudden emergence of autoantibodies that neutralise factor V, a critical cofactor in ...

Genetic research in Sweden has unveiled three new gene variants that dramatically increase the risk of venous blood clots, sometimes by up to 180%. These discoveries build on existing knowledge of ...

You might have heard that “you can't choose your family,” and the same applies to the genes you inherit from them. Everyone is born with two copies of the factor V (pronounced “factor five”) gene.

The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.