A protein that normally fosters tissue repair instead acts to inhibit healing when sugar levels are high. The role reversal helps explain why wounds heal slowly in people with diabetes. A protein that ...
The biological significance of FOXO1, a member of the forkhead box O transcription factor family, in gastric cancer (GC) remains unclear. The present study provides direct evidence of the role of ...
The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for ...
These days, lymphomas, leukemias, and other kinds of cancers can be effectively treated using chimeric antigen receptor T cell (CAR T) therapies. Now, new research from scientists at Children’s ...
The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for ...
Reactive oxygen species damage various cell components including DNA, proteins, and lipids, and these impairments could be a reason for severe human diseases including atherosclerosis. Forkhead box O1 ...
Pulmonary hypertension is characterised by uncontrolled division of cells in the blood vessel walls. As a result, the vessel walls become increasingly thick. Scientists have discovered that ...
ScienceDaily (June 29, 2012) — A recent study led by researchers at Boston University School of Medicine (BUSM) revealed that the FOXO1 gene may play an important role in the pathological mechanisms ...
A University of South Florida (USF Health) preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. The research, published July 15 in The ...
Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi ...
As a normal aspect of energy metabolism, cells in the kidney, much like those in the liver, respond to insulin by suppressing the metabolic pathways by which glucose is generated and released. In the ...
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