Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in ...

Another potentially game-changing discovery has come out of the lab of Feng Zhang, PhD. This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

Since the bacterial-origin CRISPR-Cas system rose to popularity as a genome editing tool, scientists have wondered whether other genome editors exist in nature. Now, two independent research teams ...

Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life. This year, University of Paris-Saclay biologist ...

Breakthroughs, discoveries, and DIY tips sent every weekday. Terms of Service and Privacy Policy. A team of researchers has uncovered a new biological editing system ...

Building on its success against COVID-19, mRNA technology holds promise for novel vaccines and treatments targeting various diseases. However, a critical challenge remains: current in vitro ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for ...