A seminal paper by Miller and Brody [1] clearly laid the general framework on why we should abandon the term "clinical equipoise" in research. Their paper argued that the concept of equipoise (also ...
Clinical equipoise, or uncertainty about which treatment is best for a patient, is widely viewed as essential for an ethical RCT. The authors argue that clinical trials that violate equipoise are ...
Discordance in Human Epidermal Growth Factor Receptor 2 (HER2) Phenotype Between Primary Tumor and Circulating Tumor Cells in Women With HER2-Negative Metastatic Breast Cancer Central to the argument ...
The 2016 CIOMS International ethical guidelines for health‐related research involving humans states that ‘health‐related research should form an integral part of disaster response’ and that, ...
Journal of Medical Ethics, Vol. 40, No. 8 (August 2014), pp. 576-577 (2 pages) In August 2011, a group of medical doctors, ethicists, academic and medical physicists were asked to debate and reach ...
For more than a decade, the U.S. Preventive Services Task Force (USPSTF) [23] has published a ranking of clinical evidence. [24] The rankings, however, are based on what clinical investigators have ...
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