Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the future of gene editing.

A new method for safely inserting large chunks of DNA into genomes has now measured up in mice, potentially paving the way ...

Researchers have engineered a new class of adenine base editors that reduce unwanted bystander mutations by two to three ...

INSTALL results showed successful and safe non-viral insertion of large genetic payloads in the livers of mice when delivered by lipid nanoparticles (LNPs). In contrast, mice experienced fatal immune ...