Desensitization is an important mechanism curtailing the activity of ligand-gated ion channels (LGICs). Although the structural basis of desensitization is not fully resolved, it is thought to be ...
Figure 1: Sequence and domain organization of the GluA2 receptor. The GluA2 receptor in the present study contained residues K393 to K817, which make up the LBD, the LBD–TMD linkers and the TMD (Fig.
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