Patrick Dempsey speaks out on a heartbreaking reunion that ‘couldn’t happen’ with former Grey’s Anatomy co-star Eric Dane.

From the first elevator glance to moments that reshaped television drama, Patrick Dempsey’s run as Derek Shepherd left an emotional imprint defined by romance, ambition, and the quiet weight of ...

The hints of a Derek Shepherd replacement finally being revealed in Grey’s Anatomy season 21 make the return of one sidelined feature of the medical drama possible in season 22. Derek’s relationship ...

If you haven't seen Thursday's "Grey's Anatomy" and plan to — SPOILER ALERT! Out of nowhere, the episode walloped viewers with the shocking exit of — wait for it — Derek "McDreamy" Shepherd, the ...

It's a McDream come true. Patrick Dempsey's Derek Shepherd made a shocking return in the season premiere of ABC's "Grey's Anatomy," sending longtime viewers into a frenzy on Thursday night over the ...

Dempsey, who played Dr Derek Shepherd on ‘Grey’s Anatomy’, appeared on Thursday’s episode of ‘Jimmy Kimmel Live!’ where he spoke about the show’s enduring popularity ...