Isolation of mutagen-sensitive Chinese hamster cell lines by replica plating / Małgorzata Z. Zdzienicka -- Complementation assays adapted for DNA repair/deficient keratinocytes / Mathilde Fréchet ... ...
A researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders. Researchers ...
Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.
Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...
New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair
Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair ...
New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair
XPC protein acts as a sensor to detect various abnormalities in the DNA structure. The faithful repair of DNA is ensured by using the basal transcription factor TFIIH and XPA protein to verify the ...
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