A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends ...
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...
How a mismatch between the virus’s codon usage and the host's genome can hinder viral translation.
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