Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown ...
Heat Shock Factor 1 (HSF1) is a pivotal transcription factor that orchestrates the cellular response to proteotoxic and various other forms of stress. By regulating a comprehensive transcriptional ...
For the first time, scientists believe they've discovered a cause of multiple types of birth defects triggered by environmental stresses. The breakthrough made by scientists at the Victor Chang ...
The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching effects regarding immune responses, inflammatory processes, and diseases. A ...
The article begins by introducing SGs as cytoplasmic ribonucleoprotein granules formed through phase separation in response to stress. It discusses SGs’ roles in RNA metabolism, translation regulation ...
Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...
Researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along ...
Precancerous cells must adapt to and overcome cellular stress and inflammation in order to progress and form malignant tumors. Now, researchers at University of California San Diego School of Medicine ...
The body’s cells respond to stress—toxins, mutations, starvation or other assaults—by pausing normal functions to focus on conserving energy, repairing damaged components and boosting defenses. If the ...