In 2012, a Japanese research group discovered that human skin cells acquire pluripotency when introduced to lactic acid bacteria (lactobacillus acidophilus) (Ohta et al., PLOS ONE e51866, 2012). Now, ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

Tiny cellular machines called ribosomes build proteins. When this building process goes awry in bacteria, ribosomes collide, triggering the arrival of a first responder molecule that begins a rescue ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...

This study is led by Prof. Ren Sun (Westlake University) and research fellow Yushen Du (Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine). Myelotoxicity is the ...

Research finds that the cellular assembly line that produces proteins can stall with age, triggering a snowball effect that increases the output of misfolded proteins. In humans, clumps of misfolded ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...