In tissue engineering, the tiniest bit of improper force can harm a living culture. Spheroids—3D clumps of cells—can be used ...

Just as the human body relies on organs such as the heart or liver for essential functions, cells depend on their own tiny ...

Increasingly complex cell therapy modalities, including multi-edit knock-in/knockout designs, are accelerating adoption of ...

A new study published in Engineering provides mechanistic insights into live-cell glycocalyx engineering and supports the rational design of next-generation adoptive cell therapies (ACTs) against B ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Cell and gene therapies (CGT) continue to advance in the pharmaceutical industry. Despite continued investment in R&D, the ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

Cell transfection is an important technique for various cell engineering applications, and researchers use various transfection methods for different purposes. Electroporation is among such techniques ...

Advanced therapeutics, such as cell engineering, gene therapy, and immune engineering, comprise the next generation of life-enhancing and curative interventions. As new therapies gain approval, the ...