Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

Roswell Park Comprehensive Cancer Center postdoctoral researcher Catherine Rono studies how metabolic stress in myeloid cells ...

Researchers identified invasive early disseminated cancer cells and immunosuppressive macrophage signaling that promote ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

The study will assess the tolerability, safety, maximum tolerated dose, and the recommended Phase II dose of PLT012.

Tumor metabolomics is an emerging field focused on understanding the metabolic alterations that occur in tumor cells and their surrounding microenvironment. These changes are essential to support the ...

Hyeyoung Nam, Ph.D., professor in the UAB Department of Urology, has been published in Science Advances alongside corresponding author, Sunil Sudarshan, M.D. and colleagues Richard L. Kirkman and ...

Up to 80 percent of patients with cancer struggle with cachexia, often called wasting syndrome, which is a condition characterized by the inability to gain or maintain body weight. One of the reasons ...